Human Thyroid Peroxidase ( TPO )
20 mM Tris, 250 mM NaCl, 5 % Glycerol (v/v),1 mM PMSF and 0.09 % (w/v) Sodium Azide, pH- 8.0 ± 0.2
DescriptionThyroid Peroxidase (TPO) represents one of the main auto antigenic targets in autoimmune thyroid disease of humans. Its identity with the formerly so-called ‘microsomal antigen’ has been shown several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two identical subunits of approximatly100 kDa molecular weight. Recombinant human TPO is expressed in mammalian cells and purified by using conventional chromatography.
Source: Recombinant (Mammalian Cells)
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