Cancer antigen 125 (CA 125)
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Cancer antigen 125 (CA 125)
CA 125 is a protein that in humans is encoded by the MUC16 gene and is a member of the mucin family glycoproteins. CA 125 is a potential tumor marker or biomarker for detection of ovarian cancer
Host Species
Mouse
Target Species
Human
Purity
>95%
Format
Liquid
Source
Human Fluids
Application
Feasible for controls and calibrators in immunoassays
Purity Analysis
Part pure; Low cross contamination for CA 72-4, CA 15-3, CA 19-9, CEA, AFP and Ferritin is observed and cross contaminants are reported as activity of cross contaminants/activity of CA 125 in U/ml. The passing criteria is < 25 %, however, YBL tries to restrict the levels to < 10 % for cross contamination
Immunological Activity
Immunoactivity is checked by ECLIA (Roche-Cobas)
Presentation
Liquid in 50mM Phosphate buffer, 150mM Sodium Chloride pH 7.2 – 7.6 and 0.09 % Sodium Azide
Donor Status
Healthy/Diseased
Storage
2-8°C in working aliquots
Other Information
CA 125 is stable for 3 years at 2-8°C
Viral Testing
The viral marker test negative for HBs-Ag, Anti-HCV, Anti-HIV (I and II) using CLIA (US-FDA approved). The antigen is also tested for the absence of viral DNA/RNA for HBV, HIV (I) and HCV using PCR technology
Material Safety Note
This product is not for human/animal consumption. Use only in in vitro research or products. All bio-safety precautions must be practiced while handling. Discard (if needed) as per local environmental regulation
