Cancer antigen 15-3 (CA 15-3)
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Cancer antigen 15-3 (CA 15-3)
CA 15-3 is derived from the MUC1 gene and overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers. CA 15-3 is used as an important marker for cancer detection particularly breast cancer
Host Species
Mouse
Target Species
Human
Purity
>95%
Format
Liquid
Source
Human Fluids
Application
Feasible for controls and calibrators in immunoassays
Purity Analysis
Part pure; Low cross contamination for CA 125, CA 19-9, CA 72-4, CEA, AFP and Ferritin is observed and cross contaminants are reported as activity of cross contaminants/activity of CA 15-3 in U/ml. The passing criteria is < 25%, however, YBL tries to restrict the levels to < 10 % for cross contamination
Immunological Activity
Immunoactivity is checked by ECLIA (Roche-Cobas)
Presentation
Liquid in 50mM Phosphate buffer & 150mM Sodium Chloride pH 7.2 -7.6 containing 0.09 % Sodium-Azide
Donor Status
Healthy/Diseased
Storage
2-8°C in working aliquots
Other Information
CA 15-3 part pure is stable for 3 years at 2-8°C
Viral Testing
The viral marker test negative for HBs-Ag, Anti-HCV, Anti-HIV (I and II) using CLIA (US-FDA approved). The antigen is also tested for the absence of viral DNA/RNA for HBV, HIV (I) and HCV using PCR technology
Material Safety Note
This product is not for human/animal consumption. Use only in in vitro research or products. All bio-safety precautions must be practiced while handling. Discard (if needed) as per local environmental regulation
