Cancer antigen 72-4 (CA 72-4)
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Cancer antigen 72-4 (CA 72-4)
CA 72-4 is a glycoprotein found on the surface of cancer cells and belongs to the Mucin family. Its elevated levels in the serum are associated with various carcinomas particularly gastrointestinal and gynecological cancer
Host Species
Mouse
Target Species
Human
Purity
>95%
Format
Liquid
Source
Human Fluids
Application
Feasible for controls and calibrators in immunoassays
Purity Analysis
Part pure; Low cross contamination for CA 125, CA 15-3, CA 19-9, CEA, AFP and Ferritin is observed and cross contaminants are reported as activity of cross contaminants/activity of CA 72-4 in U/ml. The passing criteria is < 25 %, however, YBL tries to restrict the levels to < 10 % for cross contamination
Immunological Activity
Immunoactivity is checked by ECLIA (Roche-Cobas)
Presentation
Liquid in 50mM Phosphate buffer & 150mM Sodium Chloride pH 7.2 -7.6 containing 0.09 % Sodium Azide
Donor Status
Healthy/Diseased
Storage
2-8°C in working aliquots
Other Information
CA 72-4 is stable for 2 years at 2-8°C
Viral Testing
The viral marker test negative for HBs-Ag, Anti-HCV, Anti-HIV (I and II) using CLIA (US-FDA approved). The antigen is also tested for the absence of viral DNA/RNA for HBV, HIV (I) and HCV using PCR technology
